Nekoko is a small, squeaky-voiced catgirl who is often seen wearing a nurse's outfit and wielding a giant syringe. She has blue eyes, short pale hair and roses cheeks. Her nurse outfit consists in pale pink shoes, white stockings, pink dress and white cap.
She appears to fit the stereotypical, cheerful catgirl archetype, but it is later revealed that she was the subject and victim of horrible medical experiments, which is most likely what made her an Orochi follower. Some flashbacks show Nekoko strapped to a chair and looking horrified as she's about to be injected with something by a bunch of doctors.
She made her debut in episode 1 when the Orochi arrives. In episode 3 she attacked the miko and was about to kill them but Soma arrived just in time to save them. Nekoko had clashed with Soma but was defeated. Also, before this, she cured Girochi's wounds from his previous fight with Soma. Nekoko is usually seen in every episode talking with the necks. In episode 7 she attacked the miko again along with Reiko, Girochi and Corona but they all are defeated by Soma . Later, when Chikane became an orochi, she is killed by her. But she is somehow alive at the end of episode 12, and is shown tending to cats happily in a square.
Nekoko's syringe contains some form of medication that can heal injuries and sickness, but the injection causes horrible pain, as noted by Girochi . Alternatively, Nekoko can launch the syringe like a rocket, carrying the same kind of kinetic charge displayed by Tsubasa 's knives, Corona's lipsticks and Reiko's fountain pens.
Her mech, Izuhara no Tamazuchi, nicknamed Meow Meow (Nya Nya), is a large mechanical ball with many cannons on it that are capable of destroying buildings easily. Chillingly, Nekoko went on a rampage that wound up destroying several Japanese landmarks, acting the whole time like a stereotypical cute little girl having fun.
- There is some indication that she carries the mark of Orochi on her bottom.
- Her first name means "cat child".